Difference between revisions of "Executive variant or frontal AD"
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* Executive dysfunction and behavioral symptoms (Salardini 2019) | * Executive dysfunction and behavioral symptoms (Salardini 2019) | ||
− | * Shares overlaps with | + | * Shares overlaps with [[behavioral variant frontotemporal dementia]], though frontal AD can be distinguished by: (Ljubenkov and Miller 2016) |
** greater burden of parietal and mesial temporal atrophy | ** greater burden of parietal and mesial temporal atrophy | ||
** greater degree of memory disturbance and executive dysfunction earlier in their course | ** greater degree of memory disturbance and executive dysfunction earlier in their course |
Latest revision as of 10:35, 12 June 2021
- Executive dysfunction and behavioral symptoms (Salardini 2019)
- Shares overlaps with behavioral variant frontotemporal dementia, though frontal AD can be distinguished by: (Ljubenkov and Miller 2016)
- greater burden of parietal and mesial temporal atrophy
- greater degree of memory disturbance and executive dysfunction earlier in their course
- less severe behavioral disturbances
- FDG-PET may help distinguish areas of hypometabolism
- amygdaloid biomarkers provide most definitive diagnostic clarity
References
Salardini, A. An Overview of Primary Dementias as Clinicopathological Entities. Semin. Neurol. 39, 153–166 (2019). https://pubmed.ncbi.nlm.nih.gov/30925609/
Ljubenkov, P. A. & Miller, B. L. A Clinical Guide to Frontotemporal Dementias. FOCUS 14, 448–464 (2016). https://pubmed.ncbi.nlm.nih.gov/31975825/