Difference between revisions of "Deep brain stimulation (DBS)"
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Treatment of major depressive disorder has been studied in subcallosal deep brain stimulation. A blinded controlled trial failed to produce significant difference between active and sham stimulation at a 6-month endpoint. Authors argue that when looking at a longer timeline (18-24 months) in an open-label study there is greater observed benefit, which persists > 8 years later. (Crowell et al, 2019). | Treatment of major depressive disorder has been studied in subcallosal deep brain stimulation. A blinded controlled trial failed to produce significant difference between active and sham stimulation at a 6-month endpoint. Authors argue that when looking at a longer timeline (18-24 months) in an open-label study there is greater observed benefit, which persists > 8 years later. (Crowell et al, 2019). | ||
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== References == | == References == | ||
Crowell, A. L. et al. Long-Term Outcomes of Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression. Am. J. Psychiatry 176, 949–956 (2019). [https://pubmed.ncbi.nlm.nih.gov/31581800/ PubMed link] | Crowell, A. L. et al. Long-Term Outcomes of Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression. Am. J. Psychiatry 176, 949–956 (2019). [https://pubmed.ncbi.nlm.nih.gov/31581800/ PubMed link] | ||
Latest revision as of 06:43, 25 June 2021
Treatment of major depressive disorder has been studied in subcallosal deep brain stimulation. A blinded controlled trial failed to produce significant difference between active and sham stimulation at a 6-month endpoint. Authors argue that when looking at a longer timeline (18-24 months) in an open-label study there is greater observed benefit, which persists > 8 years later. (Crowell et al, 2019).
References
Crowell, A. L. et al. Long-Term Outcomes of Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression. Am. J. Psychiatry 176, 949–956 (2019). PubMed link
