Executive variant or frontal AD

Revision as of 10:34, 12 June 2021 by Geoffrey (talk | contribs) (Created page with "* Executive dysfunction and behavioral symptoms (Salardini 2019) * Shares overlaps with bvFTD, though frontal AD can be distinguished by: (Ljubenkov and Miller 2016) ** greate...")
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
  • Executive dysfunction and behavioral symptoms (Salardini 2019)
  • Shares overlaps with bvFTD, though frontal AD can be distinguished by: (Ljubenkov and Miller 2016)
    • greater burden of parietal and mesial temporal atrophy
    • greater degree of memory disturbance and executive dysfunction earlier in their course
    • less severe behavioral disturbances
    • FDG-PET may help distinguish areas of hypometabolism
    • amygdaloid biomarkers provide most definitive diagnostic clarity


References

Salardini, A. An Overview of Primary Dementias as Clinicopathological Entities. Semin. Neurol. 39, 153–166 (2019). https://pubmed.ncbi.nlm.nih.gov/30925609/

Ljubenkov, P. A. & Miller, B. L. A Clinical Guide to Frontotemporal Dementias. FOCUS 14, 448–464 (2016). https://pubmed.ncbi.nlm.nih.gov/31975825/