Amyloid PET

Amyloid PET is positive in most early onset Alzheimer dementia, it is more helpful to confirm diagnosis in EOAD than LOAD because most patients in EOAD age range are not expected to have age-associated brain amyloid deposition (Mendez 2019).

References

Mendez, M. F. Early-onset Alzheimer Disease and Its Variants: Contin. Lifelong Learn. Neurol. 25, 34–51 (2019). https://pubmed.ncbi.nlm.nih.gov/30707186/