Medial Prefrontal Cortex

Dorsomedial Prefrontal Cortex

  • Associated with mentalizing (appraisal of others’ mental states), attempting to anticipate others’ behaviors (Dixon et al, 2017; Hampton et al, 2008).


Ventromedial Prefrontal Cortex

  • Associated with value estimating to assist in guiding choices (Dixon et al, 2017)
  • Emotion regulation and altering behavior in response to changing environmental conditions (Delgado et al, 2016)


Rostral PFC – may mediate appraisal of one’s own mental state / self-related information (Dixon et al, 2017)


References

Delgado, M. R. et al. Viewpoints: Dialogues on the functional role of the ventromedial prefrontal cortex. Nat. Neurosci. 19, 1545–1552 (2016). https://pubmed.ncbi.nlm.nih.gov/27898086/

Dixon, M. L., Thiruchselvam, R., Todd, R. & Christoff, K. Emotion and the prefrontal cortex: An integrative review. Psychol. Bull. 143, 1033–1081 (2017). https://pubmed.ncbi.nlm.nih.gov/28616997/

Hampton, A. N., Bossaerts, P. & O’Doherty, J. P. Neural correlates of mentalizing-related computations during strategic interactions in humans. Proc. Natl. Acad. Sci. 105, 6741–6746 (2008). https://pubmed.ncbi.nlm.nih.gov/18427116/

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